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Invariant structural core found by TOPOFIT protein structure alignment |
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TOPOFIT Reference: Valentin A. Ilyin, Alexej Abyzov, and Chesley M.Leslin, Structural alignment of proteins by a novel TOPOFIT method, as a superimposition of common volumes at a topomax point. (preprint) Protein Science (2004), 13:1865-1874. |
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T-DB Reference: Chesley M.Leslin, Alexej Abyzov, and Valentin A. Ilyin, TOPOFIT-DB, a database of protein structural alignments based on the TOPOFIT method. (accepted). Nucleic Acids Research |
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TOPOFIT DATABASE (T-DB, release 0.9) contains 86,033,950 structural alignments between all proteins in the PDB as of July 2005 found by the TOPOFIT method. Structure neighbors to the query protein structure can be retrieved by the PDB code and chain id. Pairwise or multiple structural alignments can be visualized in 3D with the FRIEND software (T-DB pages are under construction, any comments are welcome). (example output) |
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